Detail
LncRNA Name | CCAT1 |
Synonyms | CCAT1, CARLo-5, onco-lncRNA-40 |
Region | GRCh38_8:127207382-127219268 Sequence |
Ensembl | ENSG00000247844 |
RefSeq | NR_108049 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✔ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | gastric cancer |
ICD-0-3 | C16 |
Methods | qPCR, Western blot, in vitro knockdown etc. |
Sample | gastric cancer tissues |
Expression Pattern | up-regulated |
Function Description | In the present study, a great upregulation of CARLo-5 was observed in gastric cancer compared to paired adjacent normal tissues. Knockdown of CARLo-5 in gastric cancer cell lines significantly inhibited the cell proliferation via inducing G0/G1 cell-cycle arrest and apoptosis. |
Pubmed ID | 25674211 |
Year | 2015 |
Title | Enhanced expression of long noncoding RNA CARLo-5 is associated with the development of gastric cancer. |
External Links |
Links for CCAT1 | GenBank HGNC lncrnadb Noncode |
Links for gastric cancer | Omim Cosmic |
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