Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name CCAT1
   Synonyms CCAT1, CARLo-5, onco-lncRNA-40
   Region GRCh38_8:127207382-127219268    Sequence
   Ensembl ENSG00000247844
   RefSeq NR_108049
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colorectal cancer
   ICD-0-3 C19.9  
   Methods qPCR etc.
   Sample CRC tissues
   Expression Pattern up-regulated
   Function Description

The expression of IncRNA-CCAT1 in tumor tissue was significantly higher than that in normal para-carcinoma tissue, and the expression level of CCAT1 was significantly correlated with local infiltration depth , tumor staging, vascular invasion and CA19-9 level, it mediates the EMT process of colorectal cancer.

   Pubmed ID 26064266
   Year 2015
   Title Expression of lncRNA-CCAT1, E-cadherin and N-cadherin in colorectal cancer and its clinical significance.
   External Links
   Links for  CCAT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  colorectal cancer Omim       Cosmic

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