Lnc2Cancer

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   LncRNA Name CCAT1
   Synonyms CCAT1, CARLo-5, onco-lncRNA-40
   Region GRCh38_8:127207382-127219268    Sequence
   Ensembl ENSG00000247844
   RefSeq NR_108049
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name hepatocellular carcinoma
   ICD-0-3 C22.0  M8170/3
   Methods qPCR etc.
   Sample HCC tissues, cell lines (L-02, HepG2, SNU423, SMMC-7721, Hep3B)
   Expression Pattern up-regulated
   Function Description

The results indicated that the expression of CCAT1 was significantly increased in HCC tissues and cells compared with controls. We also found that the abnormally expressed CCAT1 could promote cell proliferation, migration and invasion. Taken together, our findings demonstrated that the aberrant expression of CCAT1 promotes hepatocellular carcinoma in vitro

   Pubmed ID 26191246
   Year 2015
   Title CCAT1 promotes hepatocellular carcinoma cell proliferation and invasion
   External Links
   Links for  CCAT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  hepatocellular carcinoma Omim       Cosmic

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