Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name CCAT1
   Synonyms CCAT1, CARLo-5, onco-lncRNA-40
   Region GRCh38_8:127207382-127219268    Sequence
   Ensembl ENSG00000247844
   RefSeq NR_108049
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name thyroid cancer
   ICD-0-3 C73.9  
   Methods qPCR, Western blot
   Sample cell line FTC-133
   Expression Pattern up-regulated
   Function Description

The results suggested that CCAT1 was up-regulated in the FTC-133 cells. CCAT1 suppression decreased FTC-133 cell viability, proliferation, migration, invasion, and miR-143 expression, while it increased apoptosis and VEGF expression.

   Pubmed ID 29791590
   Year 2018
   Title lncRNA CCAT1 promotes cell proliferation, migration, and invasion by down-regulation of miR-143 in FTC-133 thyroid carcinoma cell line
   External Links
   Links for  CCAT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  thyroid cancer Omim       Cosmic

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