Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name CCAT1
   Synonyms CCAT1, CARLo-5, onco-lncRNA-40
   Region GRCh38_8:127207382-127219268    Sequence
   Ensembl ENSG00000247844
   RefSeq NR_108049
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name cervical cancer
   ICD-0-3 C53  
   Methods qPCR, Western blot etc.
   Sample cervical cancer tissues, cell lines (HeLa, CaSki)
   Expression Pattern up-regulated
   Function Description

the expression of CCAT-1 in cervical cancer tissue was significantly upregulated.Kaplan-Meier survival analysis showed that recurrence-free survival of the low-CCAT-1 group was significantly higher than that of the high-CCAT-1 group.

   Pubmed ID 28978096
   Year 2017
   Title CCAT-1 promotes proliferation and inhibits apoptosis of cervical cancer cells via the Wnt signaling pathway.
   External Links
   Links for  CCAT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  cervical cancer Omim       Cosmic

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