Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

Cancer centric

Advanced search

Drug resistant

Circulating

Prognosis

Detail


   LncRNA Name ACTN4
   Synonyms ACTN4, ACTININ-4, FSGS, FSGS1
   Region GRCh38_19:38647649-38731583    Sequence
   Ensembl ENSG00000130402
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name clear cell renal cell carcinoma
   ICD-0-3 C64.9  M8005/0
   Methods microarray, qPCR etc.
   Sample RCC tissues
   Expression Pattern down-regulated
   Function Description

Four noncoding intronic transcripts mapping to intronic regions of protein-coding genes, SND1 (regulation of transcription), ACTN4 (regulation of apoptosis and of progression through cell cycle), HDAC5 (regulation of transcription and of progression through cell cycle) and NIBP (enhancer of NF-kappa-B activation) were selected for real time RT-PCR experiments; down-regulation of intronic RNAs was confirmed for transcripts mapping to introns of SND1 and ACTN4 loci in RCC tumors relative to adjacent nontumor tissues.

   Pubmed ID 18348187
   Year 2008
   Title Identification of protein-coding and intronic noncoding RNAs down-regulated in clear cell renal carcinoma.
   External Links
   Links for  ACTN4 GenBank       HGNC       lncrnadb       Noncode
   Links for  clear cell renal cell carcinoma Omim       Cosmic

CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.