Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name CCAT2
   Synonyms CCAT2, LINC00873, NCCP1
   Region GRCh38_8:127400399-127402150    Sequence
   Ensembl ENSG00000280997
   RefSeq NR_109834
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name small cell lung cancer
   ICD-0-3 C56.9  M8441/3
   Methods qPCR, Cell proliferation assay, Cell migration and invasion assay etc.
   Sample SCLC tissues, cell lines (DMS-53, H446, 16HBE)
   Expression Pattern up-regulated
   Function Description

CCAT2 expression was elevated in SCLC tissues and cell lines, and correlated with malignant status and poor prognosis of SCLC patients. Furthermore, knockdown of CCAT2 expression effectively suppressed SCLC cell growth and metastasis in vitro.

   Pubmed ID 27470400
   Year 2016
   Title LncRNA CCAT2 predicts poor prognosis and regulates growth and metastasis in small cell lung cancer.
   External Links
   Links for  CCAT2 GenBank       HGNC       lncrnadb       Noncode
   Links for  small cell lung cancer Omim       Cosmic

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