Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name CCAT2
   Synonyms CCAT2, LINC00873, NCCP1
   Region GRCh38_8:127400399-127402150    Sequence
   Ensembl ENSG00000280997
   RefSeq NR_109834
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name esophageal squamous cell cancer
   ICD-0-3  
   Methods qPCR etc.
   Sample ESCC tissues
   Expression Pattern up-regulated
   Function Description

CCAT2 was upregulated in ESCC tissues, especially in cases with lymph node metastasis (LNM), advanced TNM stages, and MYC amplification. Furthermore, the level of CCAT2 was positively correlated with TNM stages, LNM, and the number of positive lymph nodes. High CCAT2 expression and MYC amplification were significantly associated with TNM stages and LNM. CCAT2 may have great potential prognostic value for assessing postoperative ESCC patients.

   Pubmed ID 25919911
   Year 2015
   Title Elevated expression of CCAT2 is associated with poor prognosis in esophageal squamous cell carcinoma.
   External Links
   Links for  CCAT2 GenBank       HGNC       lncrnadb       Noncode
   Links for  esophageal squamous cell cancer Omim       Cosmic

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