Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name CCAT2
   Synonyms CCAT2, LINC00873, NCCP1
   Region GRCh38_8:127400399-127402150    Sequence
   Ensembl ENSG00000280997
   RefSeq NR_109834
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name gastric cancer
   ICD-0-3 C16  
   Methods qPCR, RNAi etc.
   Sample gastric cancer tissues, cell lines (BGC-823, SGC-7901, AGS, MKN-45, HGC-27 etc.)
   Expression Pattern up-regulated
   Function Description

Expression levels of lncRNA CCAT2 in gastric cancer tissues were significantly higher than those in adjacent non-tumor tissues. By statistical analyses, high lncRNA CCAT2 expression was observed to be closely correlated with higher incidence of lymph node metastasis and distance metastasis. Moreover, patients with high lncRNA CCAT2 expression had shorter overall survival and progression-free survival compared with the low lncRNA CCAT2 group.

   Pubmed ID 25755774
   Year 2015
   Title Long non-coding RNA CCAT2 is up-regulated in gastric cancer and associated with poor prognosis.
   External Links
   Links for  CCAT2 GenBank       HGNC       lncrnadb       Noncode
   Links for  gastric cancer Omim       Cosmic

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