Detail
| LncRNA Name | CCND2-AS1 |
| Synonyms | NA |
| Region | GRCh38_12:4248765-4276184 Sequence |
| Ensembl | ENSG00000255920 |
| RefSeq | NR_125790 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | glioma |
| ICD-0-3 | M9380/3 |
| Methods | qPCR, RNAi, Western blot, Luciferase reporter assay etc. |
| Sample | glioma tissues, cell lines (U87, U251, HA) |
| Expression Pattern | up-regulated |
| Function Description | We found that lncRNA CCND2-AS2 is significantly up regulated in malignant glioma tissues and cell lines. Both loss- and gain-functions assays show that CCND2-AS1 promotes glioma cells proliferation and growth. In addition, we also revealed that highly expressed CCND2-AS1 could enhance Wnt/B-catenin signaling in glioma. |
| Pubmed ID | 27923660 |
| Year | 2017 |
| Title | Highly expressed lncRNA CCND2-AS1 promotes glioma cell proliferation through Wnt/B-catenin signaling. |
| External Links |
| Links for CCND2-AS1 | GenBank HGNC lncrnadb Noncode |
| Links for glioma | Omim Cosmic |
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