Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

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   LncRNA Name CRALA
   Synonyms NA
   Region NA    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name breast cancer
   ICD-0-3 C50  
   Methods qPCR etc.
   Sample breast tissues
   Expression Pattern up-regulated
   Function Description

CRALA is upregulated in chemoresistant breast cancer cell lines compared to their parental lines. Silencing of CRALA in chemoresistant breast cancer cells resensitizes the cells to chemotherapy in vitro. Furthermore, univariate and multivariate analysis showed that higher CRALA expression was significantly associated with poor prognosis in 144 breast cancer patients.

   Pubmed ID 28834648
   Year 2017
   Title Long non-coding RNA CRALA is associated with poor response to chemotherapy in primary breast cancer
   External Links
   Links for  CRALA GenBank       HGNC       lncrnadb       Noncode
   Links for  breast cancer Omim       Cosmic

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