Detail
LncRNA Name | CRCAL-3 |
Synonyms | NA |
Region | NA Sequence |
Ensembl | NA |
RefSeq | NA |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | colorectal cancer |
ICD-0-3 | C19.9 |
Methods | RNA-seq, qPCR, in vitro knockdown |
Sample | colorectal tissue, Colon cancer cell lines (HCT116 and SW620) |
Expression Pattern | up-regulated |
Function Description | Knockdown of CRCAL-3 and CRCAL-4 in colon cancer cells reduced cell viability and colony formation ability, and induced cell cycle arrest. TCGA dataset supported the associations of CRCAL-3 and CRCAL-4 with cell cycle and revealed a co-expression network comprising dysregulated lncRNAs associated with protein-coding genes. |
Pubmed ID | 29330370 |
Year | 2018 |
Title | A RNA-Sequencing approach for the identification of novel long non-coding RNA biomarkers in colorectal cancer. |
External Links |
Links for CRCAL-3 | GenBank HGNC lncrnadb Noncode |
Links for colorectal cancer | Omim Cosmic |
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