Detail
| LncRNA Name | CRNDE |
| Synonyms | CRNDE, CRNDEP, LINC00180, NCRNA00180, PNAS-108, lincIRX5 |
| Region | GRCh38_16:54845189-54929189 Sequence |
| Ensembl | ENSG00000245694 |
| RefSeq | NA |
| Circulating | ✘ |
| Drug-resisitant | ✔ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | lung adenocarcinoma |
| ICD-0-3 | C34 M8140/3 |
| Methods | qPCR, Western blot, RIP |
| Sample | lung adenocarcinoma tissues, cell lines (A549, H1299) |
| Expression Pattern | up-regulated |
| Function Description | In our present study, we identified that CRNDE was significantly upregulated in LAD tissue and radio-resistant LAD cell lines. And high level of CRNDE expression was significantly correlated with poor differentiation, TNM stage and lymph node metastasis, radiotherapy response and high level of CRNDE expression had a significantly shorter overall survival. |
| Pubmed ID | 28550688 |
| Year | 2017 |
| Title | Long Noncoding RNA CRNDE/PRC2 Participated in the Radiotherapy Resistance of Human Lung Adenocarcinoma Through Targeting p21 Expression |
| External Links |
| Links for CRNDE | GenBank HGNC lncrnadb Noncode |
| Links for lung adenocarcinoma | Omim Cosmic |
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