Detail
LncRNA Name | CRNDE |
Synonyms | CRNDE, CRNDEP, LINC00180, NCRNA00180, PNAS-108, lincIRX5 |
Region | GRCh38_16:54845189-54929189 Sequence |
Ensembl | ENSG00000245694 |
RefSeq | NA |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✔ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | gastric cancer |
ICD-0-3 | C16 |
Methods | qPCR, Western blot, RNAi, Luciferase reporter assay |
Sample | gastric cancer tissues, cell lines (SGC7901, BGC823, MGC803, AGS) |
Expression Pattern | up-regulated |
Function Description | CRNDE was highly expressed in GC cell lines and tissues. Further investigation revealed that the miR-145 target gene E2F3 was strongly expressed following CRNDE competitive molecular sponging of miR-145. |
Pubmed ID | 28490034 |
Year | 2017 |
Title | Long Noncoding RNA CRNDE Promotes Proliferation of Gastric Cancer Cells by Targeting miR-145 |
External Links |
Links for CRNDE | GenBank HGNC lncrnadb Noncode |
Links for gastric cancer | Omim Cosmic |
CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.