Detail
| LncRNA Name | CRNDE |
| Synonyms | CRNDE, CRNDEP, LINC00180, NCRNA00180, PNAS-108, lincIRX5 |
| Region | GRCh38_16:54845189-54929189 Sequence |
| Ensembl | ENSG00000245694 |
| RefSeq | NA |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, microarray, RIP, Western blotting etc. |
| Sample | cell lines (DLD1, HCT116, SW480, SW620, LoVo, LS174t, HT29) |
| Expression Pattern | up-regulated |
| Function Description | CRNDE is upregulated in CRC tissues and cell lines. High CRNDE expression is associated with poor prognosis in CRC patients. CRNDE upregulates the expression of Ras/MAPK signaling genes. |
| Pubmed ID | 28594403 |
| Year | 2017 |
| Title | Long noncoding RNA CRNDE stabilized by hnRNPUL2 accelerates cell proliferation and migration in colorectal carcinoma via activating Ras/MAPK signaling pathways |
| External Links |
| Links for CRNDE | GenBank HGNC lncrnadb Noncode |
| Links for colorectal cancer | Omim Cosmic |
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