Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name CRNDE
   Synonyms CRNDE, CRNDEP, LINC00180, NCRNA00180, PNAS-108, lincIRX5
   Region GRCh38_16:54845189-54929189    Sequence
   Ensembl ENSG00000245694
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name hepatocellular carcinoma
   ICD-0-3 C22.0  M8170/3
   Methods qPCR
   Sample hepatocarcinoma tissues, cell lines (LM3, SMMC-7721, Mhepatocarcinoma97H and Mhepatocarcinoma97L, L-02)
   Expression Pattern up-regulated
   Function Description

The results indicated that the expression levels of both lncRNA CRNDE and LINC01419 in HCC patients group were obviously higher than that in healthy. It was found that CRNDE had high sensitivity and specificity in the diagnosis of HCC.The high expression of lncRNA CRNDE and GBAP1 suggested a poor prognosis.

   Pubmed ID 29221168
   Year 2017
   Title Diagnosis, prognosis and bioinformatics analysis of lncRNAs in hepatocellular carcinoma.
   External Links
   Links for  CRNDE GenBank       HGNC       lncrnadb       Noncode
   Links for  hepatocellular carcinoma Omim       Cosmic

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