Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name CRNDE
   Synonyms CRNDE, CRNDEP, LINC00180, NCRNA00180, PNAS-108, lincIRX5
   Region GRCh38_16:54845189-54929189    Sequence
   Ensembl ENSG00000245694
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colorectal cancer
   ICD-0-3 C19.9  
   Methods qPCR, Western blot etc.
   Sample CRC tissues, cell lines (NCM460, HT-29, SW480, HCT-116, SW620, LoVo, SW48, DLD-1, Caco2 and HT-15)
   Expression Pattern up-regulated
   Function Description

high CRNDE-p and low miR-217 levels in exosomes released from CRC cells than in exosomes released from the control NCM460 cells. serum exosomal CRNDE-p and miR-217 levels show diagnostic and prognostic potential for CRC patients.

   Pubmed ID 29137379
   Year 2017
   Title Diagnostic potential of serum exosomal colorectal neoplasia differentially expressed long non-coding RNA (CRNDE-p) and microRNA-217 expression in colorectal carcinoma.
   External Links
   Links for  CRNDE GenBank       HGNC       lncrnadb       Noncode
   Links for  colorectal cancer Omim       Cosmic

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