Detail
| LncRNA Name | DANCR |
| Synonyms | DANCR, AGU2, ANCR, KIAA0114, SNHG13, lncRNA-ANCR |
| Region | GRCh38_4:52712404-52720351 Sequence |
| Ensembl | ENSG00000226950 |
| RefSeq | NR_024031 |
| Circulating | ✘ |
| Drug-resisitant | ✔ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | lung adenocarcinoma |
| ICD-0-3 | C34 M8140/3 |
| Methods | qPCR, Western blot, Luciferase reporter assay, in vitro knockdown, RNAi, RIP etc. |
| Sample | cell line (A549, H1299,H358,HBE), lung ADC tissue |
| Expression Pattern | up-regulated |
| Function Description | Differentiation antagonizing non-protein coding RNA (DANCR) was up-regulated in lung adenocarcinoma (ADC) and that the knockdown of DANCR inhibited tumour cell proliferation, migration and invasion and restored cell apoptosis rescued; cotransfection with a miR-496 inhibitor reversed these effects. |
| Pubmed ID | 29266795 |
| Year | 2017 |
| Title | LncRNA-DANCR contributes to lung adenocarcinoma progression by sponging miR-496 to modulate mTOR expression. |
| External Links |
| Links for DANCR | GenBank HGNC lncrnadb Noncode |
| Links for lung adenocarcinoma | Omim Cosmic |
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