Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name DANCR
   Synonyms DANCR, AGU2, ANCR, KIAA0114, SNHG13, lncRNA-ANCR
   Region GRCh38_4:52712404-52720351    Sequence
   Ensembl ENSG00000226950
   RefSeq NR_024031
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name triple negative breast cancer
   ICD-0-3 C50  
   Methods qPCR, Western blot,RNAi, etc.
   Sample breast cancer cell lines (MCF-7, T47D, MDA-MB-468, MDA-MB-231), TNBC tissues
   Expression Pattern up-regulated
   Function Description

In the present study, our results showed that DANCR expression was increased in TNBC tissues compared with the adjacent normal tissues using quantitative real-time PCR (qRT-PCR) in 63TNBC specimens. The correlation between lncRNA DANCR expression and the overall survival of TNBC patients. Kaplan-Meier analysis of overall survival was analyzed according to lncRNA DANCR expression levels.

   Pubmed ID 28760736
   Year 2017
   Title Targeting long non-coding RNA DANCR inhibits triple negative breast cancer progression.
   External Links
   Links for  DANCR GenBank       HGNC       lncrnadb       Noncode
   Links for  triple negative breast cancer Omim       Cosmic

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