Detail
| LncRNA Name | DBH-AS1 |
| Synonyms | DBH-AS1, NCRNA00118, BPR |
| Region | GRCh38_9:133654586-133657313 Sequence |
| Ensembl | ENSG00000225756 |
| RefSeq | NR_002783 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✔ |
| Cancer Name | neuroblastoma |
| ICD-0-3 | M9500/3 |
| Methods | qPCR etc. |
| Sample | cell line (SH-SY5Y) |
| Expression Pattern | differential expression |
| Function Description | We found that intronic and bidirectional promoter architectures are associated with rapid RA-dependent induction or repression of the corresponding lncRNAs, followed by their constant expression. At the same time, lncRNAs expressed downstream of protein-coding genes are characterized by rapid induction, followed by transcriptional repression. Quantitative RT-PCR analysis confirmed the discovered functional modes for several selected lncRNAs associated with proteins involved in cancer and embryonic development. |
| Pubmed ID | 24555823 |
| Year | 2013 |
| Title | Role of genomic architecture in the expression dynamics of long noncoding RNAs during differentiation of human neuroblastoma cells. |
| External Links |
| Links for DBH-AS1 | GenBank HGNC lncrnadb Noncode |
| Links for neuroblastoma | Omim Cosmic |
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