Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name DGCR5
   Synonyms DGCR5, LINC00037, NCRNA00037
   Region GRCh38_22:18970514-18994628    Sequence
   Ensembl ENSG00000237517
   RefSeq NR_002733
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name lung cancer
   ICD-0-3 C34  
   Methods qPCR, western blot etc.
   Sample lung cancer tissues, cell line A549
   Expression Pattern up-regulated
   Function Description

Upregulation of DiGeorge syndrome critical region gene 5 (DGCR5) predicts better lung squamous cell carcinoma prognosis; therefore, we explore the role of DGCR5 in lung cancer in our present study. DGCR5 decreased the protein level of TUSC3 by miR-873-5p which was demonstrated by Western blot and immunofluorescence.

   Pubmed ID 29790668
   Year 2018
   Title The effects of aberrant expression of LncRNA DGCR5/miRâ??873â??5p/TUSC3 in lung cancer cell progression
   External Links
   Links for  DGCR5 GenBank       HGNC       lncrnadb       Noncode
   Links for  lung cancer Omim       Cosmic

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