Detail
LncRNA Name | DGCR5 |
Synonyms | DGCR5, LINC00037, NCRNA00037 |
Region | GRCh38_22:18970514-18994628 Sequence |
Ensembl | ENSG00000237517 |
RefSeq | NR_002733 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✔ |
MiRNA | ✔ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | lung cancer |
ICD-0-3 | C34 |
Methods | qPCR, western blot etc. |
Sample | lung cancer tissues, cell line A549 |
Expression Pattern | up-regulated |
Function Description | Upregulation of DiGeorge syndrome critical region gene 5 (DGCR5) predicts better lung squamous cell carcinoma prognosis; therefore, we explore the role of DGCR5 in lung cancer in our present study. DGCR5 decreased the protein level of TUSC3 by miR-873-5p which was demonstrated by Western blot and immunofluorescence. |
Pubmed ID | 29790668 |
Year | 2018 |
Title | The effects of aberrant expression of LncRNA DGCR5/miRâ??873â??5p/TUSC3 in lung cancer cell progression |
External Links |
Links for DGCR5 | GenBank HGNC lncrnadb Noncode |
Links for lung cancer | Omim Cosmic |
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