Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name DLEU2
   Synonyms DLEU1, BCMS, BCMS1, DLB1, DLEU2, LEU1, LEU2, LINC00021, NCRNA00021, XTP6
   Region GRCh38_13:50082171-50723236    Sequence
   Ensembl ENSG00000176124
   RefSeq NR_002605
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name chronic lymphocytic leukemia
   ICD-0-3  M9823/3
   Methods qPCR etc.
   Sample blood
   Expression Pattern differential expression
   Function Description

Here, we propose a model of a multigenic pathomechanism in 13q14.3, where several tumor suppressor genes, including the miRNA genes miR-16-1 and miR-15a, are co-regulated by the two long non-coding RNA genes DLEU1 and DLEU2 that span the critical region.

   Pubmed ID 19347735
   Year 2009
   Title Chronic lymphocytic leukemia and 13q14: miRs and more.
   External Links
   Links for  DLEU2 GenBank       HGNC       lncrnadb       Noncode
   Links for  chronic lymphocytic leukemia Omim       Cosmic

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