Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name DLX6-AS1
   Synonyms DLX6-AS1, DLX6-AS, DLX6AS, Evf-2, NCRNA00212, FLJ34048
   Region GRCh38_7:96955141-97014065    Sequence
   Ensembl ENSG00000231764
   RefSeq NR_015448
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name renal cell carcinoma
   ICD-0-3 C64.9  
   Methods qPCR, Western blot, RIP, Luciferase reporter assays etc.
   Sample renal cell carcinoma tumors, cell lines (A498, ACHN, Caki-1, Caki2, 786-O and G401)
   Expression Pattern up-regulated
   Function Description

In this study, we identified an upregulated lncRNA, DLX6-AS1, in RCC tumor tissues compared with normal kidney tissues. Our data suggested that DLX6-AS1 promoted RCC cell growth and tumorigenesis via targeting miR-26a.

   Pubmed ID 28881158
   Year 2017
   Title Long noncoding RNA DLX6-AS1 promotes renal cell carcinoma progression via miR-26a/PTEN axis
   External Links
   Links for  DLX6-AS1 GenBank       HGNC       lncrnadb       Noncode
   Links for  renal cell carcinoma Omim       Cosmic

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