Detail
LncRNA Name | AFAP1-AS1 |
Synonyms | AFAP1-AS1, AFAP1-AS, AFAP1AS, LOC84740, MGC10981 |
Region | GRCh38_4:7754090-7778928 Sequence |
Ensembl | ENSG00000272620 |
RefSeq | NR_026892 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | breast cancer |
ICD-0-3 | C50 |
Methods | qPCR |
Sample | breast cancer tissues, cell lines(MDA-MB-40 231 and MCF-7) |
Expression Pattern | up-regulated |
Function Description | both genes were significantly down-regulated in Ki-67 negative tumor samples. The observed up-regulation of AFAP1-AS1 in tumor samples compared with ANCTs implies its involvement in breast cancer pathogenesis and potentiates it as a biomarker or therapeutic target. |
Pubmed ID | 29439313 |
Year | 2018 |
Title | Expression analysis of AFAP1-AS1 and AFAP1 in breast cancer. |
External Links |
Links for AFAP1-AS1 | GenBank HGNC lncrnadb Noncode |
Links for breast cancer | Omim Cosmic |
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