Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

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Detail


   LncRNA Name DMTF1v4
   Synonyms NA
   Region NA    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colon cancer
   ICD-0-3 C18  
   Methods qPCR, Western blot, etc.
   Sample colon cancer tissues, cell line (HT-29)
   Expression Pattern up-regulated
   Function Description

lncRNA DMTF1v4 promotes colon cancer cell proliferation and migration, and inhibits apoptosis by downregulating the expression of p-ERK, p-JNK, and p-p38, thus affecting the progression of colon cancer. Compared with the control group, the cell survival rate in the DMTF1v4-siRNA group was significantly decreased.

   Pubmed ID 29949153
   Year 2018
   Title Study on the function and mechanism of long non-coding RNA DMTF1v4 in the occurrence of colon cancer.
   External Links
   Links for  DMTF1v4 GenBank       HGNC       lncrnadb       Noncode
   Links for  colon cancer Omim       Cosmic

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