Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

Cancer centric

Advanced search

Drug resistant

Circulating

Prognosis

Detail


   LncRNA Name DQ192290
   Synonyms KCNE2, ATFB4, LQT5, LQT6, MIRP1
   Region GRCh38_21:34364024-34364151    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name gastric cancer
   ICD-0-3 C16  
   Methods microarray, qPCR, RNAi etc.
   Sample gastric cancer tissues
   Expression Pattern down-regulated
   Function Description

LncRNA M59227 and 3 mRNAs, PLK1, PTTG1 and VCAN, were overexpressed in GC. In contrast, the expression of 4 lncRNAs, LOC150622, AKR7 L, DQ192290 and BC040587, and 2 mRNAs, DRD5 and GDF5, were downregulated in GC.The results indicated that TUSC7 is a p53-regulated tumour suppressor that acts in part by repressing miR-23b and that TUSC7 may be a key regulatory hub in GC.

   Pubmed ID 25765901
   Year 2015
   Title Reciprocal repression between TUSC7 and miR-23b in gastric cancer.
   External Links
   Links for  DQ192290 GenBank       HGNC       lncrnadb       Noncode
   Links for  gastric cancer Omim       Cosmic

CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.