Detail
| LncRNA Name | DREH |
| Synonyms | NA |
| Region | NA Sequence |
| Ensembl | NA |
| RefSeq | NA |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 M8170/3 |
| Methods | qPCR etc. |
| Sample | HBV-associated HCC tissues, cell lines (HepG2, HepG2.2.15, Hep3B, Huh-7 and SMMC-7721) |
| Expression Pattern | down-regulated |
| Function Description | DREH was frequently downregulated in hepatitis B virus (HBV) associated HCC tissues in comparison with adjacent non-cancerous hepatic tissues, and was inversely correlated with HBx mRNA expression in HBV associated HCC. the levels of DREH were inversely correlated with hepatitis B surface antigen and tumor size in HCC tissues. The forced expression of HBx in liver cell lines resulted in a significant decrease in the expression of DREH.This decrement was significantly correlated with poor survival in HCC patients. |
| Pubmed ID | 28789433 |
| Year | 2017 |
| Title | Downregulated long non-coding RNA DREH promotes cell proliferation in hepatitis B virus-associated hepatocellular carcinoma. |
| External Links |
| Links for DREH | GenBank HGNC lncrnadb Noncode |
| Links for hepatocellular carcinoma | Omim Cosmic |
CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.