Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name DUXAP10
   Synonyms PCAN-3
   Region GRCh38_14:19294785-19337674    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name ovarian cancer
   ICD-0-3 C56.9  
   Methods qPCR
   Sample cell lines (IOSE386,HEY, HO8910 and A2780)
   Expression Pattern up-regulated
   Function Description

DUXAP10 was significantly overexpressed in ovarian cancer tissues,and its expression was positively correlated with tumor size and FIGO stage in clinical patients. DUXAP10 played a role in promoting the proliferation of ovarian cancer cells and was expected to be a predictor and a potential therapeutic target of ovarian cancer. The overall survival rate of DUXAP10 overexpressing ovarian cancer patients was significantly lower than that of DUXAP10 low expression group.

   Pubmed ID 29424918
   Year 2018
   Title Highly expressed long non-coding RNA DUXAP10 promotes proliferation of ovarian cancer.
   External Links
   Links for  DUXAP10 GenBank       HGNC       lncrnadb       Noncode
   Links for  ovarian cancer Omim       Cosmic

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