Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name DUXAP10
   Synonyms PCAN-3
   Region GRCh38_14:19294785-19337674    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name non small cell lung cancer
   ICD-0-3 C34  M8046/3
   Methods qPCR, RNAi, RIP, western blot
   Sample non small cell lung cancer tissues, cell lines (A549, H1975, SPC-A1, PC-9, H1299, H226)
   Expression Pattern up-regulated
   Function Description

Firstly, we found that DUXAP10 was significantly up-regulated in 93 human NSCLC tissues and cell lines, and increased DUXAP10 was associated with patients poorer prognosis and short survival time.

   Pubmed ID 28029651
   Year 2017
   Title The pseudogene DUXAP10 promotes an aggressive phenotype through binding with LSD1 and repressing LATS2 and RRAD in non small cell lung cancer
   External Links
   Links for  DUXAP10 GenBank       HGNC       lncrnadb       Noncode
   Links for  non small cell lung cancer Omim       Cosmic

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