Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

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   LncRNA Name DUXAP8
   Synonyms NA
   Region GRCh38_22:15784959-15829984    Sequence
   Ensembl ENSG00000206195
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name gastric cancer
   ICD-0-3 C16  
   Methods qPCR, Western blot, RIP etc.
   Sample gastric cancer tissues, cell lines (SGC7901, BGC823)
   Expression Pattern up-regulated
   Function Description

Taken together, our findings suggest that the pseudogene-derived lncRNA DUXAP8 promotes the progression of GC and is a potential therapeutic target for GC intervention. Patients with a higher level of DUXAP8 expression had a relatively poor prognosis.

   Pubmed ID 28881724
   Year 2016
   Title The pseudogene derived long noncoding RNA DUXAP8 promotes gastric cancer cell proliferation and migration via epigenetically silencing PLEKHO1 expression
   External Links
   Links for  DUXAP8 GenBank       HGNC       lncrnadb       Noncode
   Links for  gastric cancer Omim       Cosmic

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