Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name EGOT
   Synonyms EGOT, EGO, NCRNA00190
   Region GRCh38_3:4749192-4751590    Sequence
   Ensembl ENSG00000235947
   RefSeq NR_004428
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name breast cancer
   ICD-0-3 C50  
   Methods qPCR etc.
   Sample breast cancer tissues
   Expression Pattern down-regulated
   Function Description

EGOT expression was lower in breast cancer compared with the adjacent noncancerous tissues, and low levels of EGOT expression were significantly correlated with larger tumor size, more lymph node metastasis, and higher Ki-67 expression. Moreover, patients with low levels of EGOT expression showed significantly worse prognosis for overall survival. Multivariate analysis suggested that low levels of EGOT were a poor independent prognostic predictor for breast cancer patients

   Pubmed ID 26159853
   Year 2015
   Title Downregulation of the long noncoding RNA EGOT correlates with malignant status and poor prognosis in breast cancer
   External Links
   Links for  EGOT GenBank       HGNC       lncrnadb       Noncode
   Links for  breast cancer Omim       Cosmic

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