Detail
| LncRNA Name | ENSG00000244649 |
| Synonyms | LINC02086 |
| Region | GRCh38_17:48646923-48707346 Sequence |
| Ensembl | ENSG00000244649 |
| RefSeq | XR_001752925 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | pancreatic ductal adenocarcinoma |
| ICD-0-3 | C25.3 M8500/3 |
| Methods | microarray, qPCR, Cell proliferation assay etc. |
| Sample | PDAC tissues, cell lines (AsPC-1, BxPC-3, Capan-2, CFPAC-1, HPAC, MIA PaCa-2, PANC-1 and SW1990) |
| Expression Pattern | up-regulated |
| Function Description | The qRT-PCR results showed that CRNDE, NR_036488, ENSG00000244649, AFAP1-AS and UCA1 expression was significantly increased and ENSG00000218510 expression was remarkably decreased in PDAC tissues compared with paired normal pancreatic tissues. Consistent with the findings in PDAC tissues, CRNDE, NR_036488, ENSG00000244649, AFAP1-AS1 and UCA1 expression was dramatically enhanced and ENSG00000218510 reduced in all or most of 8 PDAC cell lines in relative to the nonmalignant HPDE6-C7 cells or hTERT-HPNE cells at the RNA level. |
| Pubmed ID | 27628540 |
| Year | 2016 |
| Title | Analysis of long non-coding RNA expression profiles in pancreatic ductal adenocarcinoma. |
| External Links |
| Links for ENSG00000244649 | GenBank HGNC lncrnadb Noncode |
| Links for pancreatic ductal adenocarcinoma | Omim Cosmic |
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