Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name ENST00000415582
   Synonyms ELF3-AS1
   Region GRCh38_1:202000101-202001283    Sequence
   Ensembl ENSG00000234678
   RefSeq NR_146472
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name papillary thyroid cancer
   ICD-0-3  M8260/3
   Methods microarray, qPCR etc.
   Sample blood
   Expression Pattern up-regulated
   Function Description

Compared with 131I-avid lung metastases, we discovered that two lncRNAs (ENST00000462717 and ENST00000415582) were upregulated and two (TCONS_00024700 and NR_028494) were downregulated in the non-131I-avid lung metastases of PTC. Low (ENST00000462717 and ENST00000415582) and high plasma lncRNA levels (TCONS_00024700and NR_028494) were also found to be associated with better prognosis of PTC patients with lung metastases.

   Pubmed ID 27997908
   Year 2016
   Title Circulating Long Non-Coding RNAs Act as Biomarkers for Predicting 131I Uptake and Mortality in Papillary Thyroid Cancer Patients with Lung Metastases.
   External Links
   Links for  ENST00000415582 GenBank       HGNC       lncrnadb       Noncode
   Links for  papillary thyroid cancer Omim       Cosmic

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