The Genomic Atlas of Breast Cancer — the non-coding theme

Update News

  • GABC update 2020.06.15
  • GABC update 2019.03.20
  • GABC online 2018.08.09
  • Data collection 2018.04.09

About Us

  • Steven Xi Chen:
    steven.chen@miami.edu
  • Yunpeng Zhang:
    YXZ1418@med.miami.edu
  • Peng Wang:
    wpgqy@163.com
  • Shangwei Ning:
    ningsw@ems.hrbmu.edu.cn
  • Xia Li:
    lixia@hrbmu.edu.cn

Detail


Chr chr9
start 21994778
end 22121097
lncRNA name ANRIL
entrez id 100048912
hgnc id HGNC:34341
ensg id ENSG00000240498
refseq id NR_003529
methods qPCR etc.
regulated up-regulated
function description In breast cancer, the rs11515 CG genotype is more frequent and associated with a more aggressive tumor that could be due to increased ANRIL and reduced p16 (INK4a) expression. Compared to the CC genotype, the CG genotype was associated with lower expression of CDKN2A/p16INK4a, and higher expression of ANRIL.
pubmed id 26835415
year 2016
title The rs11515 Polymorphism Is More Frequent and Associated With Aggressive Breast Tumors with Increased ANRIL and Decreased p16 (INK4a) Expression.
drug X
circulating X
survival X

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