The Genomic Atlas of Breast Cancer — the non-coding theme

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  • GABC update 2020.06.15
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  • GABC online 2018.08.09
  • Data collection 2018.04.09

About Us

  • Steven Xi Chen:
    steven.chen@miami.edu
  • Yunpeng Zhang:
    YXZ1418@med.miami.edu
  • Peng Wang:
    wpgqy@163.com
  • Shangwei Ning:
    ningsw@ems.hrbmu.edu.cn
  • Xia Li:
    lixia@hrbmu.edu.cn

Detail


Chr chr9
start 21994778
end 22121097
lncRNA name ANRIL
entrez id 100048912
hgnc id HGNC:34341
ensg id ENSG00000240498
refseq id NR_003529
methods qPCR, Luciferase reporter assay, RIP.
regulated up-regulated
function description Expression level of ANRIL was up-regulated in TNBC tumor tissue and cell lines compared to noncancerous tissue and non-TNBC cells.the up-regulated ANRIL expression was closely correlated to poor prognosis.ANRIL knockdown interfered by interference oligonucleotide could markedly suppress TNBC cells proliferation and enhance apoptosis. ANRIL overexpression modulated TNBC tumorigenesis through acting as molecular 'sponge' for miR-199a.
pubmed id 28961506
year 2017
title Long non-coding RNA ANRIL promotes carcinogenesis via sponging miR-199a in triple-negative breast cancer.
drug X
circulating X
survival V

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