Detail

Chr	chr11
start	69475567
end	69481545
lncRNA name	AP000439.3
entrez id	NA
hgnc id	NA
ensg id	ENSG00000255980
refseq id	NA
methods	qPCR etc.
regulated	up-regulated
function description	Silencing one of most prominent lncRNA, AP000439.3, resulted in inhibition of cell cycle progression and proliferation. Further study revealed AP000439.3 can regulate expression of CCND1 through enhancing estrogen receptor induction of CCND1. This fnding revealed lncRNAs may serve as important effectors of ER in regulation of gene expression and cell phenotype in breast cancer.
pubmed id	29048636
year	2017
title	Genome-wide study of ER-regulated lncRNAs shows AP000439.3 may function as a key regulator of cell cycle in breast cancer
drug	X
circulating	X
survival	X