Detail

Chr	chr16
start	11819829
end	11828845
lncRNA name	BCAR4
entrez id	400500
hgnc id	HGNC:22170
ensg id	ENSG00000262117
refseq id	NR_024049
methods	qPCR etc.
regulated	up-regulated
function description	We showed that ectopic expression of this gene, designated as breast cancer antiestrogen resistance 4 (BCAR4), caused OH-TAM resistance and anchorage-independent cell growth in ZR-75-1 cells and that the intact open reading frame was required for its function. We conclude that retroviral transfer of cDNA libraries into human breast cancer cells is an efficient method for identifying genes involved in tamoxifen resistance.
pubmed id	16778085
year	2006
title	Functional screen for genes responsible for tamoxifen resistance in human breast cancer cells.
drug	V
circulating	X
survival	V