Chr | chr16 |
start | 86565145 |
end | 86567761 |
lncRNA name | FOXC2-AS1 |
entrez id | 103752587 |
hgnc id | HGNC:50665 |
ensg id | ENSG00000260944 |
refseq id | NR_125795 |
methods | qPCR, Western blot etc. |
regulated | up-regulated |
function description | Cyclin D1 Cyclin D2, and Cyclin D3 were all partly positively modulated by FOXC2-AS1 in BC. FOXC2-AS1 may serve as a promising prognostic biomarker and therapeutic target for BC patients. FOXC2-AS1 significantly suppressed the proliferation ability and flow cytometric analysis illustrated the influence of FOXC2-AS1 on cell cycle and apoptosis rate. |
pubmed id | 29562954 |
year | 2018 |
title | Long non-coding RNA FOXC2-AS1 predicts poor survival in breast cancer patients and promotes cell proliferation |
drug | X |
circulating | X |
survival | V |
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