Detail

Chr	chr1
start	173863900
end	173868882
lncRNA name	GAS5
entrez id	60674
hgnc id	HGNC:16355
ensg id	ENSG00000234741
refseq id	NR_002578
methods	qPCR, Western blot
regulated	down-regulated
function description	Here, we show that levels of the lncRNA, growth arrest-specific transcript 5 (GAS5), are decreased in TNBC tissues, and this down-regulation of GAS5 is associated with an aggressive tumor phenotype in patients, affecting clinical stage, lymph node metastasis and overall survival. These data suggest that GAS5 can suppress TNBC progression by competitively binding miR-196a5p, therefore GAS5 may be a prognostic biomarker of TNBC.
pubmed id	29793177
year	2018
title	Long noncoding RNA GAS5 suppresses triple negative breast cancer progression through inhibition of proliferation and invasion by competitively binding miR-196a-5p
drug	X
circulating	X
survival	V