Chr | chr1 |
start | 67832303 |
end | 68202987 |
lncRNA name | GNG12-AS1 |
entrez id | 100289178 |
hgnc id | HGNC:43938 |
ensg id | ENSG00000232284 |
refseq id | NR_040077 |
methods | qPCR, RNAi, ChIP etc. |
regulated | down-regulated |
function description | We report that GNG12-AS1 is coexpressed with DIRAS3 in several tissues and coordinately downregulated with DIRAS3 in breast cancers. In breast cancer cell lines with loss of DIRAS3 imprinting, DIRAS3 and GNG12-AS1 are silenced in cis and the remaining GNG12-AS1 transcripts are predominantly monoallelic. |
pubmed id | 23871723 |
year | 2013 |
title | Imprinted chromatin around DIRAS3 regulates alternative splicing of GNG12-AS1, a long noncoding RNA. |
drug | X |
circulating | X |
survival | X |
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