The Genomic Atlas of Breast Cancer — the non-coding theme

Update News

  • GABC update 2020.06.15
  • GABC update 2019.03.20
  • GABC online 2018.08.09
  • Data collection 2018.04.09

About Us

  • Steven Xi Chen:
    steven.chen@miami.edu
  • Yunpeng Zhang:
    YXZ1418@med.miami.edu
  • Peng Wang:
    wpgqy@163.com
  • Shangwei Ning:
    ningsw@ems.hrbmu.edu.cn
  • Xia Li:
    lixia@hrbmu.edu.cn

Detail


Chr chr11
start 1995176
end 2001470
lncRNA name H19
entrez id 283120
hgnc id HGNC:4713
ensg id ENSG00000130600
refseq id NR_002196
methods Immunohistochemical Staining, ISH etc.
regulated up-regulated
function description In 72.5% of studied breast adenocarcinomas an overall H19 gene expression is increased when compared with healthy tissues. The H19 gene is generally overexpressed in stromal cells (92.2%) and rarely in epithelial cells (2.9% only). An up-regulation of the H19 gene is significantly correlated with the tumor values and the presence of both estrogen and progesterone receptors, and at the cellular level, the H19 gene demonstrates an independent expression versus accumulation of both the p53 protein and the Ki-67/MIB-1 cell-cycle marker.
pubmed id 9811352
year 1998
title H19 overexpression in breast adenocarcinoma stromal cells is associated with tumor values and steroid receptor status but independent of p53 and Ki-67 expression.
drug X
circulating X
survival X
Chr chr11
start 1995176
end 2001470
lncRNA name H19
entrez id 283120
hgnc id HGNC:4713
ensg id ENSG00000130600
refseq id NR_002196
methods Immunohistochemical Staining, ISH etc.
regulated up-regulated
function description H19 gene is generally overexpressed in stromal cells (92.2%) and rarely in epithelial cells (2.9% only), 3) an up-regulation of the H19 gene is significantly correlated with the tumor values and the presence of both estrogen and progesterone receptors, and 4) at the cellular level, the H19 gene demonstrates an independent expression versus accumulation of both the p53 protein and the Ki-67/MIB-1 cell-cycle marker.
pubmed id 9811352
year 1998
title H19 overexpression in breast adenocarcinoma stromal cells is associated with tumor values and steroid receptor status but independent of p53 and Ki-67 expression.
drug X
circulating X
survival X

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