The Genomic Atlas of Breast Cancer — the non-coding theme

Update News

  • GABC update 2020.06.15
  • GABC update 2019.03.20
  • GABC online 2018.08.09
  • Data collection 2018.04.09

About Us

  • Steven Xi Chen:
    steven.chen@miami.edu
  • Yunpeng Zhang:
    YXZ1418@med.miami.edu
  • Peng Wang:
    wpgqy@163.com
  • Shangwei Ning:
    ningsw@ems.hrbmu.edu.cn
  • Xia Li:
    lixia@hrbmu.edu.cn

Detail


Chr chr5
start 163483065
end 163494058
lncRNA name HMMR-AS1
entrez id 101927813
hgnc id HGNC:49149
ensg id ENSG00000251018
refseq id NR_109892
methods qPCR, RNAi, Luciferase reporter assay etc.
regulated up-regulated
function description We found that the expression of HMMR was positively correlated with HMMR-AS1 (RP11-80G.1). When HMMR-AS1 (RP11-80G.1) was knocked down, the expression of HMMR markedly reduced. Furthermore, in MDA-MB-231 and MDA-MB-468 breast cancer cells, the proliferation and migration abilities were remarkably suppressed via knocking down HMMR-AS1 (RP11-80G.1) in vitro.
pubmed id 27920576
year 2016
title The HMMR-AS1 expression was markedly higher in BLBCs in contrast to those in non-BLBC subtypes. HMMR antisense RNA 1, a novel long noncoding RNA, regulates the progression of basal-like breast cancer cells.
drug X
circulating X
survival X

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