Chr | chr12 |
start | 53962308 |
end | 53974956 |
lncRNA name | HOTAIR |
entrez id | 100124700 |
hgnc id | HGNC:33510 |
ensg id | ENSG00000228630 |
refseq id | NR_003716 |
methods | microarray, qPCR, ISH etc. |
regulated | up-regulated |
function description | Co-expression of HOTAIR and EZH2 trended with a worse outcome. In matched primary and metastatic cancers, both HOTAIR and EZH2 had increased expression in the metastatic carcinomas. This approach offers a method to make observations on lncRNAs that may influence the cancer epigenome in a tissue-based technique. |
pubmed id | 23133536 |
year | 2012 |
title | Detection of long non-coding RNA in archival tissue: correlation with polycomb protein expression in primary and metastatic breast carcinoma. |
drug | X |
circulating | X |
survival | V |
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