The Genomic Atlas of Breast Cancer — the non-coding theme

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  • GABC online 2018.08.09
  • Data collection 2018.04.09

About Us

  • Steven Xi Chen:
    steven.chen@miami.edu
  • Yunpeng Zhang:
    YXZ1418@med.miami.edu
  • Peng Wang:
    wpgqy@163.com
  • Shangwei Ning:
    ningsw@ems.hrbmu.edu.cn
  • Xia Li:
    lixia@hrbmu.edu.cn

Detail


Chr chr12
start 53962308
end 53974956
lncRNA name HOTAIR
entrez id 100124700
hgnc id HGNC:33510
ensg id ENSG00000228630
refseq id NR_003716
methods microarray, qPCR, ISH etc.
regulated up-regulated
function description Co-expression of HOTAIR and EZH2 trended with a worse outcome. In matched primary and metastatic cancers, both HOTAIR and EZH2 had increased expression in the metastatic carcinomas. This approach offers a method to make observations on lncRNAs that may influence the cancer epigenome in a tissue-based technique.
pubmed id 23133536
year 2012
title Detection of long non-coding RNA in archival tissue: correlation with polycomb protein expression in primary and metastatic breast carcinoma.
drug X
circulating X
survival V

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