The Genomic Atlas of Breast Cancer — the non-coding theme

Update News

  • GABC update 2020.06.15
  • GABC update 2019.03.20
  • GABC online 2018.08.09
  • Data collection 2018.04.09

About Us

  • Steven Xi Chen:
    steven.chen@miami.edu
  • Yunpeng Zhang:
    YXZ1418@med.miami.edu
  • Peng Wang:
    wpgqy@163.com
  • Shangwei Ning:
    ningsw@ems.hrbmu.edu.cn
  • Xia Li:
    lixia@hrbmu.edu.cn

Detail


Chr chr12
start 53962308
end 53974956
lncRNA name HOTAIR
entrez id 100124700
hgnc id HGNC:33510
ensg id ENSG00000228630
refseq id NR_003716
methods qPCR, RNAi, ChIP, Dual-luciferase reporter assay etc.
regulated up-regulated
function description Microscopic analysis showed that HOTAIR knockdown has suppressed the growth of MCF7 cells in comparison to the control or scramble-antisense treated cells even at 24 h of post HOTAIR siSENSE transfection. Growth analysis showed that HOTAIR knockdown has suppressed the growth of MCF7 cells significantly in comparison to the control (untreated) or scramble-antisense treated cells.
pubmed id 23375982
year 2013
title Antisense transcript long noncoding RNA (lncRNA) HOTAIR is transcriptionally induced by estradiol.
drug X
circulating X
survival X

CopyRight © University of Miami, USA; Harbin Medical University, China