Detail

Chr	chr12
start	53962308
end	53974956
lncRNA name	HOTAIR
entrez id	100124700
hgnc id	HGNC:33510
ensg id	ENSG00000228630
refseq id	NR_003716
methods	qPCR, RNAi, Western blot, Cell proliferation assay etc.
regulated	up-regulated
function description	Ten different lncRNAs were applied in this study, which was reported to be associated with Notch-1. The level of these ten lncRNAs in breast tumors and adjacent normal tissues were evaluated, which suggested that HOTAIR and MALAT1 increased most significantly, and LUNAR1 and GAS5 decreased most significantly.
pubmed id	26550436
year	2015
title	Notch-1 promotes breast cancer cells proliferation by regulating LncRNA GAS5.
drug	X
circulating	X
survival	V