Chr | chr12 |
start | 53962308 |
end | 53974956 |
lncRNA name | HOTAIR |
entrez id | 100124700 |
hgnc id | HGNC:33510 |
ensg id | ENSG00000228630 |
refseq id | NR_003716 |
methods | qPCR, Western blot |
regulated | differential expression |
function description | We discovered that knockdown of HOTAIR induced significant decrease in proliferation and increase in apoptosis of MCF-7 cells, and the cell cycles of HOTAIR siRNA transfected cells have been arrested at G1 phase (p < 0.01); |
pubmed id | 28407576 |
year | 2017 |
title | HOTAIR may regulate proliferation, apoptosis, migration and invasion of MCF-7 cells through regulating the P53/Akt/JNK signaling pathway |
drug | X |
circulating | X |
survival | X |
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