The Genomic Atlas of Breast Cancer — the non-coding theme

Update News

  • GABC update 2020.06.15
  • GABC update 2019.03.20
  • GABC online 2018.08.09
  • Data collection 2018.04.09

About Us

  • Steven Xi Chen:
    steven.chen@miami.edu
  • Yunpeng Zhang:
    YXZ1418@med.miami.edu
  • Peng Wang:
    wpgqy@163.com
  • Shangwei Ning:
    ningsw@ems.hrbmu.edu.cn
  • Xia Li:
    lixia@hrbmu.edu.cn

Detail


Chr chr17
start 72403322
end 72592804
lncRNA name LINC00673
entrez id 100499467
hgnc id HGNC:44354
ensg id NA
refseq id NR_036488
methods RNA-seq, qPCR
regulated up-regulated
function description We identified lnc00673 (ERRLR01) as a marker of overall survival (OS) in breast cancer patients.ERRLR01 levels were elevated in triple-negative breast cancer (TNBC) as compared with Luminal-A,Luminal-B, and HER2 breast cancer subtypes. ERRLR01 levels were also inversely correlated with breast cancer survival across all breast cancer patients.OS in ERa-tumors correlated with negative overall survival,while in ERa+ tumors,ERRLR01 correlated with positive outcomes.This suggests ERRLR01 is modulated by hormone signaling in breast cancer.ERRLR01 correlated with distinct pathways including epithelial development and cellular differentiation.
pubmed id 28795861
year 2017
title linc00673 (ERRLR01) is a prognostic indicator of overall survival in breast cancer.
drug X
circulating X
survival V

CopyRight © University of Miami, USA; Harbin Medical University, China