Chr | chr17 |
start | 72403322 |
end | 72592804 |
lncRNA name | LINC00673 |
entrez id | 100499467 |
hgnc id | HGNC:44354 |
ensg id | NA |
refseq id | NR_036488 |
methods | RNA-seq, qPCR |
regulated | up-regulated |
function description | We identified lnc00673 (ERRLR01) as a marker of overall survival (OS) in breast cancer patients.ERRLR01 levels were elevated in triple-negative breast cancer (TNBC) as compared with Luminal-A,Luminal-B, and HER2 breast cancer subtypes. ERRLR01 levels were also inversely correlated with breast cancer survival across all breast cancer patients.OS in ERa-tumors correlated with negative overall survival,while in ERa+ tumors,ERRLR01 correlated with positive outcomes.This suggests ERRLR01 is modulated by hormone signaling in breast cancer.ERRLR01 correlated with distinct pathways including epithelial development and cellular differentiation. |
pubmed id | 28795861 |
year | 2017 |
title | linc00673 (ERRLR01) is a prognostic indicator of overall survival in breast cancer. |
drug | X |
circulating | X |
survival | V |
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