Detail

Chr	NA
start	NA
end	NA
lncRNA name	LOC284454
entrez id	NA
hgnc id	NA
ensg id	NA
refseq id	NA
methods	RNA-seq, RT-qPCR, Western blot, in vitro knockdown, RIP
regulated	down-regulated
function description	Expression of LOC284454 is significantly reduced in breast, prostate, uterus and kidney cancer and also in breast cancer cell lines (MCF7 and T47D). Global gene expression studies upon loss and gain of function of LOC284454 revealed perturbation of genes related to cancer-related pathways. Focal adhesion and cell migration pathway genes are downregulated under overexpression condition, and these genes are significantly upregulated in breast cancer cell lines as well as breast cancer tissue samples suggesting a functional role of LOC284454 lncRNA in breast cancer pathobiology.
pubmed id	29227193
year	2017
title	DDX5/p68 associated lncRNA LOC284454 is differentially expressed in human cancers and modulates gene expression.
drug	X
circulating	X
survival	X