The Genomic Atlas of Breast Cancer — the non-coding theme

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About Us

  • Steven Xi Chen:
    steven.chen@miami.edu
  • Yunpeng Zhang:
    YXZ1418@med.miami.edu
  • Peng Wang:
    wpgqy@163.com
  • Shangwei Ning:
    ningsw@ems.hrbmu.edu.cn
  • Xia Li:
    lixia@hrbmu.edu.cn

Detail


Chr chr9
start 21455642
end 21559669
lncRNA name LOC554202
entrez id 554202
hgnc id HGNC:37187
ensg id ENSG00000171889
refseq id NR_027054
methods qPCR, RNAi, Western blot etc.
regulated up-regulated
function description We assay the expression level of lncRNAs-Loc554202 in breast cancer tissues and find that Loc554202 is significantly increased compared with normal control, and associated with advanced pathologic stage and tumor size. Moreover, knockdown of Loc554202 decreased breast cancer cell proliferation, induced apoptosis and inhibits migration/invasion in vitro and impeded tumorigenesis in vivo.
pubmed id 24631686
year 2014
title Long non-coding RNA Loc554202 regulates proliferation and migration in breast cancer cells
drug X
circulating X
survival X

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