Detail

Chr	chr11
start	65497688
end	65506516
lncRNA name	MALAT1
entrez id	378938
hgnc id	HGNC:29665
ensg id	ENSG00000251562
refseq id	NR_002819
methods	qPCR, RNAi, Western blot, Cell proliferation assay etc.
regulated	up-regulated
function description	Ten different lncRNAs were applied in this study, which was reported to be associated with Notch-1. The level of these ten lncRNAs in breast tumors and adjacent normal tissues were evaluated, which suggested that HOTAIR and MALAT1 increased most significantly, and LUNAR1 and GAS5 decreased most significantly.
pubmed id	26550436
year	2015
title	Notch-1 promotes breast cancer cells proliferation by regulating LncRNA GAS5.
drug	X
circulating	X
survival	X